This is the little guy who is telling us so much about Inflammatory Bowel Syndrome.    
Symbol:
Il10tm1Cgn
Name:
interleukin 10; targeted mutation 1, University of Cologne
MGI ID:
MGI:1857199
Synonyms:
Il10-, IL-10-, IL-10KO, IL-10KO, IL-10 KO, Il10tmCgn
Gene:

Il10  Location: Chr1:131019845-131024974 bp, + strand  Genetic Position: Chr1,

56.89 cM

Mutations:

A 500 bp genomic fragment containing codons 5-55 was replaced with a linker

containing a termination codon followed by a neomycin cassette. A termination

codon was also introduced into exon 3. No IL10 activity was detectable by ELISA

assays in supernatants of in vitro cultures of Con A-stimulated splenic T cells

derived from homozygous mice following infection with the nematode N.

brasiliensis. (J:15222)