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When Your Dog Faces Hip Dysplasia CHD

 

Ron Hines DVM PhD

Arthritis, Joint & Back Pain in Your Older Dog

 

Hip dysplasia is one of the most common skeletal diseases that our dogs face. When your dog develops hip dysplasia (CHD), it is usually the result of an inherited (genetic) tendency for the hip joints to be too lax or loose (laxity/subluxation). (ref)  This abnormal looseness is between the articulating ball of your dog's hip joint (the femoral head) and the stable pelvic socket of the hip joint, the acetabulum. Lax, unstable joints lead to inflammation, excessive wear and tear and bone remodeling. The end result is pain, joint cartilage degeneration and arthritis. I tried to show those changes in the first drawing. The second is an x-ray of a young dysplastic dog. Arthritis is not very evident in that dog - yet.

Male and female dogs suffer dysplasia in equal frequency. CHD is most often seen in the larger and giant breeds. German shepherds, Rottweilers, and St. Bernards are high on the list. When it occurs in the high-frequency breeds, it is often in the “larger than life” eye catching dogs on the top end of their breed’s size scale. 

Dog breeds that are resistant to CHD tend to be about the size of ancestral dogs. They have refined features, a long snout and a multitalented body structure designed to be swift and survive the hardships of feral life.  Wild canids like wolves, fox and jackals are also free of CHD issues.

Smaller, lighter breeds are not immune to hip dysplasia. Some (like bull dogs) have been intentionally bred for a waddley, dysplastic gait. When CHD affects them, these smaller breeds are less likely to show signs of pain, stiffness and restricted mobility. That is probably largely due to their lighter weight. But their temperament and what we expect of them factor in too.

Because CHD has a strong genetic element, it tends to occur when one or both of your dog's parents were also somewhat dysplastic - or at least carried some of the genes that predispose dogs to the problem. And because many genes are involved, we call it a polygenetic tendency or trait.

 

 

Even if your dog inherits an unfortunate combination of genes, CHD is not inevitable. That is because individual growth rate, diet, environment and neuter status exert substantial effects as well. Hip dysplasia can skip generations. It can affect some puppies in a litter while sparing others. That is what makes the problem so difficult for breeders to stamp out. (ref)

Your dog's hip joint is constructed similarly to the ball joint of your automobile - similar to this image:

This type of arrangement forms a very strong weight-bearing structure that allows great range of motion. But for the joint to work properly, the ball must be held deeply and snuggly within its socket. There are a series of very strong ligaments, fibrous and cartilaginous layers (the joint capsule) that accomplish that - when they are working properly. When they are lax, as in dysplasia, forces are applied in ways that are destructive to the living tissues that comprise the hip joint.

Because the joint is a living structure, individual bone cells response to irritation in predictable ways. The pet's hipbones slowly change their shape (remodel). They recede in the areas of increased pressure and they proliferate in the areas surrounding the pressure and irritation. The process (actually the result) is called osteoarthritis or degenerative joint disease. Some degree of osteoarthritis, including the hips, occurs in all of us and our pets as we get older; but loose joints, joints in improper alignment and joints carrying too much weight will develop the problem sooner.

There are all degrees of canine hip dysplasia. They range from very minor changes, which cause no lameness or limping, to severe cases in which the entire architecture of the joint is lost to arthritis. In these more severe cases the round ligament as well as the ligaments of the joint capsule are stretched, allowing the ball to wobble (subluxate) or for the ball of the femur to slip entirely out of the acetabulum (a luxation).

Although inherited hip dysplasia always affects both legs, whichever side bothers your dog the most on a particular day is the side that will exhibit lameness, limping and pain the most.

The bone surfaces within the hip joint that touch each other are coated with a slick hyaline cartilage coating. In a normal joint, they are very smooth, slick and cushioned with a shock absorbing underlayer of more fibrous cartilage. In dysplastic joints, these layers have eroded off, allowing painful bone-to-bone contact.

When unprotected bone rubs on bone, the bone surfaces under pressure dissolve while new bone (osteophytes) form adjacent to it (on the periphery). It is a vicious, self-perpetuating cycle. The femoral head that once looked as round and smooth as a billiard ball now becomes flattened and mushroomed, with cauliflower-like new bone on its periphery (edge). The socket or acetabulum loses its normal depth (shallow acetabulum)

What Signs Might I See When My Dog Has Hip Dysplasia ?

In puppies, young or adolescent dogs, walking abnormalities are due to joint looseness itself. In mature dogs, they are more likely due to the pain of hip arthritis. It is quite rare for pain to be a large factor in their abnormal gait before six months of age.

Dysplastic puppies are born with hip joints that appear normal on x-rays. That is because the final shape of their hip joint is molded by forces associated with joint movement and walking. At 12 days of age there is no discernable difference between the hips of a dysplastic or a normal puppy. (ref1, ref2)

In puppies, you might notice a gait often referred to as “bunny hopping”, a rocking (“waddling”) motion as they walk, and perhaps some rear leg muscle weakness. They might sit more on their haunches with their legs splayed outward (but all young puppies lack coordination).

As time goes by, they might have trouble climbing stairs or navigating up slopes and they might be reluctant to jump up or over low obstacles. When pain finally does become a significant factor, they often keep their rear legs placed farther forward than normal in order to keep more weight on their front legs.

When you examine these dogs with advancing signs of hip dysplasia, their upper thighs and hips are often bony and lack muscle mass. They are often “cow-hocked”, standing with their hocks almost touching. Some of these adolescent dogs actually improve for a time as their hips reach full calcium content (ossification) and before the pain of hip arthritis becomes a major issue. In hip x-rays taken of these younger dogs, the degree of joint changes may not correlate well with the pain the dog is experiencing. Some dogs that show significant joint changes show little pain, and vice versa.

Older dogs share many of the signs I described for puppies. With time, those signs tend to intensify. In significant cases, stiffness on rising becomes a problem. Decreased activity levels compared to their peers are common as well. Disuse can cause the muscles or their hips and thighs to be smaller than their non-dysplastic peers (muscle atrophy). They often show hesitance getting in and out of cars. They might also spend more time grooming and worrying areas on their body that annoy them. Those and other low-motility endeavors are preferred. This can lead to problems such as lick granulomas (ref), elbow and other pressure calluses as well as skin sores and regional hair loss.

Since all grades of hip dysplasia occur, many dogs with mild to moderate CHD don’t begin to limp until they are 4 or 5 years old. The working breeds, can be particularly stoic and show little sign of lameness until arthritis in their hips is well advanced.

The pain in these dogs is often worse after exercise or first thing in the morning. Morning stiffness usually works out as the day progresses. These dogs would rather sit on their haunches than stand. They might not be able to keep up with you on your walks like they once did. Your dog’s problems might be worse in cold weather – particularly when it has been lying on cold cement or tile floors. As I mentioned earlier, x-rays can be misleading in these dogs since the degree of joint destruction may not correlate with the degree of pain and lameness your pet is experiencing.

How Will My Veterinarian Decide If My Pet’s Lameness Is Due To Hip Dysplasia ?

Only x-rays can positively diagnose hip dysplasia. But there are signs your veterinarian will pick up on that bring dysplasia to mind:

Your dog’s breed and size are one clue.

Your veterinarian will probably ask you to walk your dog around the office or exercise area to observe its gait. A problem here is that dogs in unfamiliar environments often hide minor to moderate lamenesses they exhibit at home.

Your vet will closely examine the whole of your dog's rear legs looking for alternative explanations for your dogs discomfort. Things like broken toenails, interdigital cysts, thorns, knee issues and the like. Fresh skin abrasions that might indicate recent hip, leg or back trauma are important to check for too.

When the vet guides your dog’s hips through a full range of motion, evidence of pain at the extremes of motion is another major clue.

Sometimes, thumb pressure over the joint will elicit (cause) pain.

When dysplasia is quite severe, downward traction might cause a popping as the head of the femur separates from the shallow acetabulum (subluxates).  The popping sound is call the Ortolani sign. I never continue with these tests without anesthesia if a dog squirms or shows any evidence of pain. I move on to x-rays with sedation and do it then. Unless your vet gets lucky and the dog is comfortable and relaxed, meaningful hip x-rays early in dysplastic disease almost always require anesthesia/sedation.

X-rays  Radiographs

X-rays of your dog’s hips will tell if your dog has hip dysplasia. In early dysplasia, when small changes can be missed, they are best read by a trained radiologist.To be of much value, the dog must be positioned in the x-ray beam just right. If the dog is even slightly off axis (cockeyed), it can appear from the x-ray that the hip is abnormal when it is not. The diagnostic position for an in-office or OFA hip dysplasia evaluation is dog with  its back on the table, rear legs extended back fully and parallel, knees rotated toward the center line (and the attending personnel shielded from radiation and outside the exposure beam of course). Done right, it should yield an image like this.The second image, here, is of a dog with considerable hip dysplasia. Notice that the ball of each femur is no longer as round as it should be. It is a young dog, so advanced arthritis changes like joint lip proliferation have not begun yet. With time, inflammation will stimulate new bone (the osteophytes I mentioned earlier) to form at the periphery of the joint causing considerable pain. The blue arrow points to that advanced process going on here.

Hip Certification

High quality x-rays of young adult dogs can be submitted to OFA where experts will make a judgment as to the dogs' hip quality. The services were developed in an attempt to lessen the incidence of hip dysplasia in the breeds most prone to it.

The OFA service began in 1966. They will review x-rays taken by your veterinarian. If the dog is over 4 months old but less than 2 years old, their decisions will be “preliminary”. (ref) When the x-rays are submitted from a dog over 2 years old, the results are a final grade as to the dog’s “hip health” in relation to what they believe to be ideal hip joint conformation.

The University of Pennsylvania School of Veterinary Medicine began an alternative program, PennHIP (the Pennsylvania Hip Improvement Program), in 1993. It is now administered by Antech Imaging Services. The motivation for the Penn program was the slow rate with which hip dysplasia was being reduced using the OFA method. (ref) The PennHIP procedure can be employed as early as 16 weeks for predicting the likelihood of future degenerative joint changes in your dog's hips. (ref) That might give dog owners time to make diet and lifestyle changes in the hope of delaying the onset of pain and debility in their pet. It might also be a wise procedure to perform when selecting a future service dog. Conscientious dog breeders also have the procedure performed before choosing which dogs to breed as well as to provide reassurance to those that purchase puppies from them.
 
Unlike the OFA, the PennHIP procedure utilizes three x-ray views of your dog's hips. Penn requires an x-ray image of the dog's hip in extended view, a compression view and a distraction view. The three are used to obtain a numerical measurement of hip joint laxity. You can see the three views here. Your dog must be anesthetized and the procedure must be performed by veterinarians certified in the program before a hip score (distraction index) can be assigned. Your dog's distraction score is based on measurements, not the subjective opinion of veterinarians - as is the OFA method is. See a PennHIP report here. Most veterinarians today believe the PennHIP approach yields a more accurate prediction of your dog’s future hip health.  The drawbacks are higher cost and the use of only veterinarians within the PennHIP network. Dog owners who fear anesthesia for their pets can usually shop around and find a vet willing to take OFA x-rays without the use of an anesthetic; that is not the case with PennHip. 
 
The AKC does not require dogs to have good hips. The AKC is strictly a beauty contest. Canine health, a pain-free life and longevity are not among their priorities. When I must present bad hip or other genetic news to my clients, it is common for them to reply, "that can't be, he came with papers !!".

What Are Things I Can Do To Avoid Or Minimize A Looming Dysplasia Problem ?

Later Neutering Of Female Dogs And Leaving Male Dogs Intact

Pediatric spaying of female dogs and castration of male dogs is partially responsible for many of the long-term health problems that plague our pets. (ref) Hip dysplasia is one of them. (ref)

Early-age neutering has profound negative effects on your dog’s bones and other organs.  It also increases the chances of obesity when dogs are fed free choice.

Growth Rate And Nutrition

Don’t over feed your puppy or growing dog. Growing dogs are capable of consuming more food than they should for optimum bone structure and health. Too rapid a growth rate and excessively fast weight gain make genetic tendencies toward hip dysplasia worse. When pups grow too quickly, the structural strength of their bones and joints can’t keep up with the rapid growth in their muscle’s mass, weight and strength. Discouraging rapid weight gain will not change your dog’s genetic predisposition to hip dysplasia. But a slower progress to adult body weight might be helpful in delaying the onset of hip dysplasia or its severity.

Dietary calcium & calcium/vitamin D supplements are unhelpful. (ref)  

Thoughtful Exercise

Your dog needs exercise to keep its hip and leg muscles strong. But do not push your young dog to over-perform. Your dog will do almost anything to please you and it cannot tell you when it is pushing the limits of its healthy endurance. You have to look out for its best interests.

Dogs that are still growing have developed strong muscles, but their bone and joint structure has not reached its maximum strength. Hip dysplasia begins with microfractures. (ref) Pups at high risk of developing hip dysplasia need a low impact lifestyle until the bones of their hips have fully ossified and the joints are less plastic to deformation. Ligaments and supporting structures of the joint also take time to reach their full potential strength. The situation is similar in horses that are raced too young. (ref)

For adult dysplastic dogs, walking them on a leash, swimming, or a slow treadmill are all fine. Don’t overdo it. Your dog should not appear worse the following day. When you take your pet for walks, stay on unpaved grassy areas that cushion their steps avoiding hard packed, paved or uneven surfaces. You need to pay attention to their toenail length. Toenails of dysplastic dogs tend to overgrow and become a danger in themselves. There might come a time when a mobility harness will be helpful as well.

Avoid Obesity

Most large breed dogs love to eat. My Labrador retriever Maxx sure does. When a dog becomes overweight and has no thyroid issues, it is not a canine problem. It is a human problem. It is always a struggle for me not to equate providing extra food with providing extra love. Resist that temptation as best you can. Carrying extra weight around puts extra stress on the skeletal support of your dog’s whole body. Even if you later decide your dog needs hip surgery, the results are likely to be considerably better if your dog is not overweight.     

Padded Bedding And Soft Relaxing/Sleeping Areas

I believe that the worst thing for a dog with hip dysplasia is sleeping on a cold, hard floor. Wood floors and carpets improve maters some. But your dog will be most comfortable on an over-stuffed dog bed or something similar. My Labrador Retriever Maxx is now 13 years old. His favorite resting and sleeping area are two black rubber mats –a commercial entrance mat placed on top of a similar size ergonomic/anti-fatigue mat (I bond them together with Loctite PL S30 adhesive). (ref)  I prefer these, rather than porous cloth or open foam products, for large dogs. They are easily washed and sanitized and harder for dogs to destroy.

Soothing Warmth

Just as with arthritis in people, some dogs are most uncomfortable in cold weather. A warm room free of drafts and a heat source – preferably a heating pad designed specifically for dogs - might be appreciated on cold nights. A wool pet sweater when out and about might also be helpful.

Physical Therapy

Physical therapy and hydrotherapy can go a long way in reducing your pet's pain and debility when dealing with hip dysplasia. Hire a professional or begin by kneading the muscles around the hips with your fingertips in gentle, circular motions. Gradually work your way around the surrounding muscles. There is an entire science of pet physical therapy, which you can explore.  Begin on YouTube.

If there comes a time when it becomes too painful for your dog to climb stairs or go outside to relieve itself there are ways to overcome those issues. Building a handicap ramp can be helpful. Some dogs can be paper-trained.

Medications

Hip dysplasia pain and debility can often be managed with medications. The disease is a form of arthritis; so the same group of medications that are helpful for us humans suffering from arthritis are often helpful to our dogs. There are no known medications that will reverse dysplasia-associated arthritis in dogs. What we have will, at best, relive pain and lessen inflammation.

Do not be tempted to reach into your medicine cabinet for medications prescribed for you and give them to your dog. Giving them to your dog could be dangerous. At the least, the dose or frequency might be wrong for a dog. At the worst, it might be a particular drug that dogs do not handel well (like aspirin) or one that is dangerous for your dog due to its concurrent medical issues. Liquid human medicine can also contain xylitol.

Non Steroidal Anti-inflammatory Drugs

NSAIDs decrease joint inflammation and pain. Some, like aspirin, ibuprofen and naproxicin are inappropriate for dogs. Some, like meloxicam (Metacam® /Mobic®), are appropriate for dogs and humans, and some, like deracoxib, firocoxib and grapiprant  (eg Deramaxx®, Previcox® and Galliprant®) are marketed specifically for veterinary use. Most dogs handle these medications just as well as humans do. When issues arise, they are usually related to stomach and intestinal tract inflammation that NSAIDs cause more frequently in dogs than humans. Always keep those issues in mind. Just because a medication works safely in most dogs doesn’t mean it will work safely in your dog. Always read the warnings on the product insert that comes with your dog’s medications. Periodic blood tests when you pet is taking these medications regularly is always wise.

Corticosteroids

Corticosteroids, like prednisone, are strongly anti-inflammatory. They will relieve arthritis pain. However, given long term, they have profound side effects. Those include weight gain due to increased appetite, liver enlargement and fluid retention, decreased ability to fight infections, slowed healing and a host of other undesirable metabolic effects. I reserve them for end of life situations where dog owners want to be with their pets just a little bit longer. 

Tramadol

Tramadol (Ultram®) is a narcotic medication that relieves pain. There are dogs that develop intestinal troubles when given NSAIDs or don't receive enough relief from them. In those cases, tramadol might be helpful. It is reasonably priced in its generic form and usually has minimal side effects when given in the proper way. Unlike NSAIDs, tramadol can be given in combination with corticosteroids.

Gabapentin

Gabapentin (Neurontin®) is another medication that sometimes helps with chronic pain. It was originally used in the treatment of epilepsy in humans, where it was noticed that it helped them with pain as well. In humans, it appeared to be more effective in pain due to nerve irritation than due to arthritis or dysplasia. But recent studies seemed to show that it decreased the pain of arthritis in experimental animals as well. (ref1, ref2 [Nociception = pain]) Gabapentin is inexpensive and has few side effects when given properly. It does not help all dysplastic dogs and when it does, it often takes several weeks before you can expect any positive effects. 

Nutraceuticals

These are products that are not evaluated by the American Food and Drug Administration (FDA) because they are considered "foods" rather than "medicines". It is very difficult to find hard data that prove that any of them work or don't work. Because dogs with hip dysplasia have good days and bad days" and because dogs can’t talk, it is very hard for anyone to get a handle on their actual effectiveness. Published reports on their effectiveness and testimonials tend to be “advertorials” by companies intent on selling you their wears.  Anything that is prefixed by the words  “complimentary” “amazing” “alternative” “miracle”, “breakthrough” or “dramatic” generally fall into this classification. Anything that claims it helps all dogs with joint mobility issues belongs there too.

Among those products are antioxidants, fish and krill oils, zinc supplements, polysufated glycosaminoglycan (Adequan®), glucosamine and chondroitin (Cosequin®), hyaluronic acid, omega-3 fatty acids, topical DMSO, Boswellia serrata, etc. etc. etc.

Platelet rich plasma injections, low-level laser therapy, acupuncture and massage therapy receive at best mixed reviews as to their benefits - although most dogs love a massage and added attention. (ref1, ref2)

Give any of these options a try if you wish; but realize that you really do not know what you are getting or where you are going when you purchase from unregulated providers. If I don’t see these products and services as proven treatments on the veterinary university websites or in the medical publications that I respect, I don't suggest them.

What Are My Dog’s Surgical Options ?

Several types of surgery can sometimes help dysplastic dogs. In adult dogs, these surgeries are designed to eliminate pain and improve mobility. My preference in heavier weight breeds is for a total hip replacement with the surgery put off as long as non-surgical options maintain the dog’s quality of life. In lighter weight dogs, my preference is still for femoral head ostectomy.

In puppies the aim is to reassemble the joint in ways that make hip dysplasia less likely to occur. Unfortunately, none of those reconstructive techniques have been adequately studied long-term for me to accurately tell you their success rates in relation to other, less drastic measures. (ref)


Read more about these procedures below:

Femoral Head Osteotomy (FHO)

Many speak of femoral head excision or osteotomy as a salvage procedure. It is true that the dog’s gait will likely not return to normal. But the dog will be pain-free and happy which is my primary concern. It is a less successful procedure in large and giant breeds of dogs (not as successful in dogs over 45 lbs/20.4Kg adult weight). To read more about femoral head excision (FHO) go here. FHO serves no purpose when the dog’s hip joints are fully luxated and the animal already pain-free. It is a real joy to me to see these pets running pain-free and happy again.

A Hip Replacement

Artificial hip joints (prostheses) perform well in dogs. Their gait often returns to near normal and they remain pain-free. Some veterinary orthopedic surgeons prefer devices that are bonded to the bone with special cements, others prefer cement-free techniques.

One drawback is expense. The 2019 cost given by Ohio State Veterinary School for the procedure is $5,600 – $6,000 per hip + $200-$300 per follow up visit. However, they state that “Four out of five dogs or 80% of their patients with arthritis in both hips only require that one side be operated upon to return them to a satisfactory and comfortable life”.  Veterinary surgeons rarely suggest hip replacements before a dog is fully-grown. The hip bones of your dog need to be at their maximum size, tissues fully developed and fully calcified in order for the prosthetic joint to hold fast and function optimally. Dogs generally stay 3-5 days at the facility after their surgery. After their surgery, activity is generally limited for 2-3 months. This gives time for complete healing; but procedures and techniques differ depending on the individual proclivities (inclinations) of your dog's surgeon.

Surgically Changing The Alignment of Your Dog’s Hip Sockets

Triple Or Double Pelvic Osteotomy Or Symphysiodesis (TPO, DPO, JPS) 

If a puppy or adolescent dog still has some growing to do, procedures exist that attempt to reassemble the dog’s acetabulum (hip socket) in positions that might promote joint stability. The two most common techniques, TPO and DPO, cut the bone that forms your dog’s hip socket (acetabulum) into three or two sections and reassembles them in positions designed to hold the head of the femur more snugly in the joint socket.

There has not been enough long-term tracking of dogs after TPO, DPO or JPS surgery for me to be confident in predicting the results of any of the three procedures. The only attempts I know of were done in 2007 and 2010. The first study noted that the procedures had not eliminate hip joint laxity or the progression of hip joint arthritis when examined 2 years after the surgery. (ref)  The second study found improvement was still present two years after JPS surgery. (ref)  Surgical procedures are rarely questioned until something better comes along. In the case of canine hip dysplasia, nothing has. Many university veterinary orthopedic centers and veterinary orthopedists offer the TPO or DPO procedures.

The University of Wisconsin Veterinary School pioneered the symphysiodesis (JPS) technique. In that procedure, one growth plate of your pup’s pelvis (the pubic symphysis [ref] )  is prematurely prevented from growing - as it normally would until your dog reached its full size.  Click on the image above. The red line outlines the pubic symphysis area. Since the other centers for pelvic growth continue to grow, the shape of your dog’s pelvis changes and so do the forces that press the head (ball) of the femur into the acetabulum (socket). Of the three procedures, this is the least traumatic and least expensive - but I noted that the University of Wisconsin Veterinary School no longer mentions the JPS technique on their website. Instead, in 2019, they promote only total hip replacements. You would have to call them about that. If you do, let me know their answer.

Fifteen to 20 weeks of age would probably be the ideal time to perform the JPS procedure. (rptref) That is a very small window of opportunity. At that tender age, the only reliable method to determine if your puppy needed the procedure would be the PennHIP test that I previously mentioned.

TPOs and DPOs are generally suggested between 6 and 12 months of age. If performed on your dog much younger, the pet's bone structure might not be strong enough to hold the required anchoring screws and plates. When performed much beyond a year of age, self-perpetuating arthritic joint changes and remolding that this surgery cannot correct have already begun. So again, the time window for hoped-for success is quite short.

If you have had any of these procedures performed on your dog and have kept track of dysplastic litter mates that received no surgery; or if you just want to comment on the success of any of these surgeries in your dog, I am sure that other readers would appreciate your insights. Let me know and as time allows I will post your messages here